教育工作经历

2011.09 ~ 2015.07   陕西师范大学          应用化学        学士 导师：刘昭铁教授和陈建刚副教授

2015.09 ~ 2017.02 beoplay体育提现      生物医学工程         硕士（转博）导师：王忠良教授

2017.02 ~ 2021.12 beoplay体育提现    生物信息科学与技术       博士 导师：王忠良教授

2022.01 ~ 至今   beoplay体育提现            华山准聘副教授（讲师）

2022.10 ~ 至今   beoplay体育提现                       在职博士后                              合作导师：田捷教授

学术交流经历

2016.09 ~ 2017.01 中科院自动化研究所分子影像重点实验室田捷教授团队 访问学生

2022.03 ~ 至今   香港中文大学（深圳）理工学院唐本忠院士团队 访问学者

文章情况

2023年

1.   Qian Jia^#, Ruili Zhang^#, Haohao Yan^#, Yanbin Feng, Fang Sun, Zuo Yang, Chaoqiang Qiao, Xiaocheng Mou, Jie Tian and Zhongliang Wang^*. An Activatable Near-Infrared Fluorescent Probe for Precise Detection of the Pulmonary Metastatic Tumors: A Traditional Molecule Having a Stunning Turn. Angewandte Chemie International Edition, 2023, e202313420. (Received, DOI: 10.1002/anie.202313420. VIP论文)

2.  Zhiping Rao, Yutian Xia, Qian Jia, Yutong Zhu, Lexuan Wang, Guohuan Liu, Xuelan Liu, Peng Yang, Pengbo Ning, Ruili Zhang, Xianghan Zhang, Chaoqiang Qiao^*, Zhongliang Wang^*. Iron-Based Metal-Organic Framework Co-Loaded with Buthionine Sulfoximine and Oxaliplatin for Enhanced Cancer Chemo-ferrotherapy via Sustainable Glutathione Elimination. Journal of Nanobiotechnology, 2023, 21(1):265.

3.  Zhuang Chen, Weijing Liu, Zuo Yang^*, Yi Luo, Chaoqiang Qiao, Anna Xie, Qian Jia, Peng Yang, Zhongliang Wang^*, Ruili Zhang^*. Sonodynamic-Immunomodulatory Nanostimulators Activate Pyroptosis and Remodel Tumor Microenvironment for Enhanced Tumor Immunotherapy. Theranostics, 2023, 13(5):1571 – 1583.

2022年

1.  Qian Jia^#, Ruili Zhang^#, Yongdong Wang, Haohao Yan, Zheng Li, Yanbin Feng, Yu Ji, Zuo Yang, Yang Yang^*, Kanyi Pu, Zhongliang Wang^*. A Metabolic Acidity-Activatable Calcium Phosphate Probe with Fluorescence Signal Amplification Capabilities for Non-Invasive Imaging of Tumor Malignancy. Science Bulletin, 2022, 67(3): 288 – 298. (IF = 11.78, JCR1, Top) DOI:10.1016/j.scib.2021.11.003

2. Shaohua Qu^#, Qian Jia^#, Zheng Li, Zhongliang Wang^*, Li Shang^*. Chiral NIR-II fluorescent Ag₂S quantum dots with stereospecific biological interactions and tumor accumulation behaviors. Science Bulletin, 2022, 67(12): 1274 – 1283. (IF = 11.78, JCR1, Top) DOI:10.1016/j.scib.2022.05.001

3.      Jie Yu^#, Ruili Zhang^#, Baihang Chen^#, Xuelan Liu, Qian Jia, Xiaofei Wang, Zuo Yang, Pengbo Ning*, Zhongliang Wang*, Yang Yang*. Injectable Reactive Oxygen Species-Responsive Hydrogel Dressing with Sustained Nitric Oxide Release for Bacterial Ablation and Wound Healing, Advanced Functional Materials, 2022, 32, 2202857.

4. Zuo Yang^#, Chaoqiang Qiao^#, Qian Jia, Zhuang Chen, Xiaofei Wang, Xuelan Liu, Ruili Zhang, Kanyi Pu, Zhongliang Wang. Redox dyshomeostasis modulation of the tumor intracellular environment through a metabolic intervention strategy for enhanced photodynamic therapy. Theranostics, 2022, 12(14): 6143 – 6154. (IF = 11.600, JCR1, Top) DOI: 10.7150/thno.75837.

5. Chaoqiang Qiao^#, Zuo Yang^#, Xuelan Liu^#, Ruili Zhang, Yuqiong Xia*, Lexuan Wang, Zhuang Chen, Qian Jia, Ruhao Wang, Yang Yang*, Zhongliang Wang*. Post-Remedial Oxygen Supply: A New Perspective on Photodynamic Therapy to Suppress Tumor Metastasis. Nano Letters, 2022, 22(20): 8250 – 8257.

6.  Zhuang Chen, Weijing Liu, Zuo Yang*, Yi Luo, Chaoqiang Qiao, Anna Xie, Qian Jia, Peng Yang*, Zhongliang Wang*, Ruili Zhang*，Sonodynamic-Immunomodulatory Nanostimulators Activate Pyroptosis And Remodel Tumor Microenvironment for Enhanced Tumor Immunotherapy. Theranostics, 2023, 13(5):1571 – 1583.

2021年

1.  Qian Jia^#, Zheng Li^#, Mingli Bai, Haohao Yan, Ruili Zhang^*, Yu Ji, Yanbin Feng, Zuo Yang, Zhongliang Wang^*, and Jianxiong Li^*. Estimating Dynamic Vascular Perfusion Based on Er-based Lanthanide Nanoprobes with Enhanced Down-Conversion Emission Beyond 1500 nm. Theranostics, 2021, 11(20): 9859 – 9872. (IF = 11.556, JCR1, Top) DOI:10.7150/thno.65771

2.  Yutao Zhang, Chenxu Yan, Qiaoqiao Zheng, Qian Jia, Zhongliang Wang, Ping Shi, Zhiqian Guo*. Harnessing Hypoxia-Dependent Cyanine Photocages for In Vivo Precision Drug Release. Angewandte Chemie International Edition, 2021, 60(17):9553 – 9561. (IF = 15.336, JCR1, Top) DOI:10.1002/anie.202017349

3. Chaoqiang Qiao^#, Xiaofei Wang^#, Guohuan Liu, Zuo Yang, Qian Jia, Lexuan Wang, Ruili Zhang, Yuqiong Xia*, Zhongliang Wang*, Yang Yang*. Erythrocyte Membrane Camouflaged Metal-Organic Framework Nanodrugs for Remodeled Tumor Microenvironment and Enhanced Tumor Chemotherapy. Advanced Functional Materials, 2021, 2107791. (IF = 18.808, JCR1, Top) DOI:10.1002/adfm.202107791

4. Jie Yu^#, Hua Xiao^#, Zuo Yang^#, Chaoqiang Qiao^#, Bin Zhou^#, Qian Jia, Zhongdi Wang, Xiaofei Wang, Ruili Zhang*, Yang Yang*, Zhongliang Wang* and Jianxiong Li*. A Potent Strategy of Combinational Blow Toward Enhanced Cancer Chemo-Photodynamic Therapy via Sustainable GSH Elimination. Small, 2021, 2106100. (IF = 13.281, JCR1, Top) DOI:10.1002/smll.202106100

2020年

1.  Chaoqiang Qiao^#, Ruili Zhang^#, Yongdong Wang^#, Qian Jia^#, Xiaofei Wang, Zuo Yang, Tengfei Xue, Renchuan Ji, Xiufang Cui, Zhongliang Wang^*. Rabies Virus-Inspired Metal-Organic Frameworks for Targeted Imaging and Chemotherapy of Glioma. Angewandte Chemie International Edition, 2020, 59(39): 16982 – 16988. (IF = 15.336, JCR1, Top) DOI:10.1002/anie.202007474

2.  Ruili Zhang^#, Linlin Wang^#, Xiaofei Wang, Qian Jia, Zhuang Chen, Zuo Yang, Renchuan Ji, Jie Tian, and Zhongliang Wang*. Acid-Induced In Vivo Assembly of Gold Nanoparticles for Enhanced Photoacoustic Imaging-Guided Photothermal Therapy of Tumors. Advanced Healthcare Materials, 2020, e2000394. (IF = 9.933, JCR1, Top) DOI: 10.1002/adhm.202000394

3.  Na Zhao*, Yue Li^#, Wei Yin^#, Jiabao Zhuang, Qian Jia, Zhongliang Wang, and Nan Li*. Controllable Coumarin-Based NIR Fluorophores: Selective Subcellular Imaging, Cell Membrane Potential Indicating and Enhanced Photodynamic Therapy. ACS Applied Materials & Interfaces, 2020, 12,2,2076 – 2086. (IF = 9.229, JCR1, Top) DOI:10.1021/acsami.9b18666

2019年

1. Ruili Zhang^#, Chaoqiang Qiao^#, Qian Jia^#, Yongdong Wang, Huimin Huang, Wanwan Chang, He Wang, Hao Zhang, Zhongliang Wang^*. Highly Stable and Long-Circulating Metal-Organic Frameworks Nanoprobes for Sensitive Tumor Detection In Vivo. Advanced Healthcare Materials, 2019, 8(19): e1900761. (IF = 9.933, JCR1, Top) DOI: 10.1002/adhm.201900761

专利情况

1.   Zhongliang Wang, Yongdong Wang, Ruili Zhang, Qian Jia, Chaoqiang Qiao, Jie Tian. pH-Responsive Ultrasensitive Fluorescent Nanoprobe, Preparation and Using Method Thereof. 美国发明专利，US 11,291,736 B2 [P]. 授权公告日2021.12.02.

2.   王忠良， 乔晁强， 张瑞丽， 王永东， 贾茜， 常湾湾， 薛腾飞， 纪仁川， 崔秀芳， 田捷. 一种基于仿生狂犬病毒的纳米诊疗制剂及其制备方法与应用: 中国发明专利, ZL 201910389661.0 [P]. 授权公告日2021.09.17.

3.   张瑞丽，王忠良， 王永东， 白明利， 袁慧娟， 贾茜，闫如玉， 田捷. 上转换纳米粒子非氧依赖性光动力学诊疗探针及制备方法: 中国发明专利，ZL 201810925419.6 [P]. 授权公告日2021.09.14.

4.   王忠良， 常湾湾， 张瑞丽， 王中嫡， 王琳琳， 黄慧敏， 贾茜，乔晁强， 陈柏行. 一种用于肿瘤药物深入递送的温敏型纳米药物制剂及其制备方法与应用: 中国发明专利, ZL 201910033393.9 [P]. 授权公告日2021.09.06.

5.   王忠良， 张瑞丽， 贾茜， 王永东. 一种光敏复合薄膜材料及其制备方法和应用: 中国发明专利，ZL 201610793922.1 [P]. 授权公告日2019.04.30.

获奖情况

1.2018年，第四届“i创达人”科技创新创业计划大赛全国总决赛全国九强。

2.2019年，中国肿瘤学大会青年优秀论文奖。

3.2019年，陕西高校青年创新团队–“多模态分子影像创新团队”成员。

4.2019年，第四届“校长杯”创新创业大赛校内选拔银奖。

5.2019年，beoplay体育提现“优秀研究生”荣誉称号。

6.   2019年，第四届beoplay体育提现“三好三有”研究生导学团队成员。

7.2019年，beoplay体育提现生命科学技术学院学术年会口头报告评比一等奖。

8.2019年，beoplay体育提现生命科学技术学院学术年会论文评比三等奖。

9.2021年“陕西省科技工作者创新创业大赛一等奖。

10.2022年“分子影像与肿瘤精准诊疗”陕西省科技创新团队成员。